Study explores weight gain with HIV treatment

– Study by Kaiser Permanente researchers highlights weight gain in HIV patients undergoing antiretroviral therapy (ART).

– Comparison with demographically similar non-HIV individuals revealed greater weight gain among those with HIV over a 2-year period.

– Lead author Jennifer Lam, PhD, underscores the rigorous analysis utilizing a large healthcare dataset to account for various health conditions impacting weight change.

– 8,256 HIV patients and 129,966 non-HIV individuals from 3 Kaiser Permanente regions were included, matched by sex, age, and race or ethnicity.

– Annual BMI increase was significantly higher in HIV patients (0.53 kg/m2) compared to non-HIV individuals (0.12 kg/m2) post-ART initiation.

Weight gain patterns varied slightly by ART medication class, with integrase inhibitors and protease inhibitors showing higher increases compared 

– While weight gain is common early in HIV treatment, BMI typically stabilizes after the initial 2-year period.

Importance stressed on healthcare providers monitoring HIV patients' weight and cardiometabolic health

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