HKDC1's Role: Protein HKDC1 aids in maintaining mitochondria and lysosomes, crucial for cell health.
Mitophagy Assistance: HKDC1's interaction with TOM20, an outer mitochondrial protein
Lysosomal Repair: HKDC1's localization in mitochondria is critical for lysosomal repair; reduced HKDC1 disrupts lysosomal cleanup
VDAC Interaction: HKDC1's role involves interacting with VDACs, proteins linking mitochondria and lysosomes
Preventing Cellular Senescence: HKDC1's multifaceted functions prevent cellular aging and maintain organelle integrity.
Therapeutic Potential: Understanding HKDC1's pivotal role opens new therapeutic avenues targeting age-related diseases linked to organelle malfunction